In Vitro and In Vivo Anti Hyperglycemic Evaluation of Sterculia quadrifida Bark through The Inhibition of Alpha Glucosidase

Data from the International Diabetes Federation revealed annual increases in prevalence of diabetes mellitus, which require special attention. Implementation ‘back to nature’ trend presents opportunities overcome this problem. As a medicinal plant, Faloak is widely used by people Nusa Tenggara Timur, Indonesia. This study aimed evaluate vivo and vitro anti-hyperglycemic activity bark Sterculia quadrifida, known as Faloak. In evaluation sucrose-induced male mice. Measurements glucose level employed glucometer data were analyzed statistically. Demonstrating decoct, results showed doses 1.67 3.3 g/kg BW reduced levels 62.2% 56.9%, respectively. examination decoct at various concentrations alpha glucosidase (sucrose) enzymatic reaction. Results examinations demonstrated inhibited 42.09 ± 4.39%. Further testing on humans needed confirm these findings.